The purpose of the research was to design and validate the supplementary curriculum model compatible with the brains of ADHD students. This research was a mixed, exploratory type in the qualitative part of document analysis, qualitative content analysis and interviews with 17 experts, and in the quantitative part, a questionnaire with 10 components and 180 sub-components were designed and implemented with 40 experts in curriculum planning, psychology, and brain sciences. Based on the feedback, the questionnaire was modified and given to 419 experts in curriculum planning, psychology, brain science, education experts, counseling and elementary school teachers in Mashhad. The validity of the questionnaire was confirmed by experts, and the validity and reliability of the data were confirmed by means of member checks and Cronbach's alpha (0.83). A qualitative, targeted sampling method was used in the quantitative part of the multi-stage cluster sampling method. Structural equation modeling analysis was used to validate the model and it was confirmed by first-order factor analysis. The results of the second-order confirmatory factor analysis showed that the 11 components (logic, goals, content, learning teaching strategies, evaluation, learning environment, materials and resources, teacher's role, learning time, grouping, and inclusive characteristics) have sufficient factor loading. To predict the brain-compatible supplemental curriculum pattern of students with ADHD. Also, the indexes (CMIN/DF = 0.842), RMSEA = 0.000, CFI = 1.000, TLI = 1.005, IFI = 1.003) and RFI = 974 Was. The results showed that the designed model has a very favorable fit.